http://jsfiddle.net/CtH9k/
div {
width: 250px;
height: 100px;
line-height: 100px;
text-align: center;
border: 1px solid #123456;
padding:20px;
}
span {
display: inline-block;
vertical-align: middle;
line-height: normal;
}
<div>
<span>Lorem ipsum dolor sit amet, consectetur adipiscasdfsadfsadfsdafsadfasdfasding elit.</span>
</div>
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